Ketamine相关论文
目的:评价艾司氯胺酮用于乳腺癌改良根治术老年患者术后自控静脉镇痛的效果。方法:择期全麻下行乳腺癌改良根治术女性患者90例，年龄......
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Effects of Ketamine on Basal Gamma Band Oscillation and Sensory Gating in Prefrontal Cortex of Awake
Gamma band oscillation (GBO) and sensory gating (SG) are associated with many cognitive functions.Ketamine induces defic......
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Background: Ketamine is a controlled substance and often illegally used as a recreational drug primarily by young adults......
Loss of Phenotype of Parvalbumin Interneurons Contrib utes to the Antidepressant Effects of Ketamine
Depression is a highly prevalent disorder and currently available antidepressants have delayed onset of actions with low......
Neuropsychopharmacology of ketamine as a rapid-acting agent on depression and suicidal ideation in d
Ketamine is classified as a dissociative anesthetic agent for anesthesia and pain control,and used as an experimental to......
Ketamine is a highly attractive candidate for developing fast-onset antidepressant agents; however,the relevant brain ci......
Neonatal Ketamine Exposure Causes Impairment of Long-term Synaptic Plasticity in the Anterior Cingul
Ketamine,a dissociative anesthetic most commonly used in many pediatric procedures,has been reported to cause widespread......
Rapid and long-lasting antidepressant effects of Yueju are associated with its instant and lasting d
Accumulating evidence indicated that N-methyl-D-aspartate(NMDA)receptors are involved in the pathophysiology of depressi......
The rapid antidepressant effect of ketamine is associated with the down-regulation of pro-inflammato
Objectives.Active inflammatory responses play an important role in the pathogenesis of depression.We hypothesized that t......
Inhibition of L-arginine-nitric oxide pathway mediates the antidepressant-like effects of ketamine o
Converging evidence has shown that acute administration of ketamine in a sub-anaesthetic dose exerts fast-acting and rob......
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氯胺酮是一种离子型谷氨酸能N-甲基-D-天冬氨酸受体（glutamatergic N-methyl-D-aspartate receptor, NMDAR）拮抗剂，具有快速且持久的......
氯胺酮是非竞争性NMDA受体拮抗剂，用作分离性麻醉药已有很长历史，近年研究表明氯胺酮可能有神经保护作用，可以改善患者的认知功能。文......
<strong>Background</strong>: Inpatient subanaesthetic ketamine infusion for 5 days may improve pain and reduce oral opio......
HDAC6 is critical for ketamine-induced impairment of dendritic and spine growth in GABAergic project
Ketamine is widely used in infants and children for anesthesia;both anesthetic and sub-anesthetic doses of ketamine have......
Regulation of mTORC1 signaling network underlying the pathophysiology and treatment of depression ne
Depression is a devastating mental disorder and major depressive disorder afflictsabout 16% of the world population ......
Pain in chronic pancreatitis(CP) shows similarities with other visceral pain syndromes(i.e.,inflammatory bowel disease a......
小儿外科手术是临床常见手术,由于患儿大多难以合作,局部麻醉很难进行手术,常常选择全身麻醉。由于手术时间相对较短,多采用保留自......
AIM To evaluate the safety and efficacy of sedating pediatric patients for outpatient flexible bronchoscopy.METHODS A re......
Effects of ketamine on mouse hippocampal inflammatory cytokines IL-6,IL-1β and TNF-α levels in acute
OBJECTIVE Ketamine is an injectable anesthetic and recreational drug of abuse commonly used worldwide. Many experimental......
氯胺酮（ketamine）是一种具有深度镇痛的静脉全麻药，临床上主要用于各种中、小型手术。但在用药过程中，有时可产生精神副作用，尤其是视觉......
Taobao,QQ,and designer drug companies fi nd loopholes,customers,and solace in the anonymity of the World Wide Web在中国,......
目的 探讨多次氯胺酮麻醉对未成年大鼠记忆能力的影响及其可能机制.方法 21日龄筛选合格SD大鼠64只,分为氯胺酮组(包括k1和k7两个......
目的 探讨单次氯胺酮注射对孕鼠子代在空间认知能力、探索能力方面的行为学改变.方法 3月龄SD同胞雌大鼠12对,用随机数字表法分为4......
目的观察磷酸二酯酶-4抑制剂Ro 20-1724对幼年大鼠反复氯胺酮麻醉后社会交往能力的影响。方法32只21日龄大鼠，采用随机数字表法分为......
目的比较氯胺酮依赖者和甲基苯丙胺依赖者的睡眠质量状况及影响因素。方法采用自编吸毒者一般情况调查表、匹兹堡睡眠质量指数量表......
目的探讨短期低剂量褪黑素与氯胺酮对慢性应激抑郁模型大鼠抑郁样行为及前额叶脑源性神经营养因子(brain-derived neurotrophic fa......
目的探讨预防性皮下注射氯胺酮对瑞芬太尼诱导大鼠痛觉过敏的治疗作用及对脊髓背角钾氯共转运体-2(K＋/Cl－cotransporter 2，KCC2)表达......
目的探讨氯胺酮对产前束缚应激子代大鼠不同发育阶段的抑郁样行为的影响。方法随机选择怀孕的SD母鼠分成对照组(n＝6)和产前束缚应激......
目的探讨丙泊酚复合小剂量氯胺酮在小儿眼科手术中的应用价值。方法选取66例ASA I~II级择期实施小儿眼科手术的病人,随机分成研究......
氯胺酮单次滴注有7～10天的持续抗抑郁和显著降低自杀风险效应，但其具体机制尚不明确。本文对氯胺酮持续抗抑郁效应机制进行综述，发现......
N-methyl-D-aspartate receptor expression in the spinal dorsal horn of a rat model of formalin-induce
Clinical and animal experiments have proved that intrathecal injection of butorphanol has an analgesic effect. However, ......
Ketamine inhibits c-Jun protein expression in mouse hippocampus following cerebral ischemia/reperfus
A model of cerebral ischemia and reperfusion was established in mice. Mice were treated with ketamine via intraperitonea......
Male Wistar 7-day-old rats were injected with 40 mg/kg ketamine intraperitoneally, followed by three additional injectio......
目的 观察不同剂量苏芬太尼复合小剂量氯胺酮在术后静脉自控镇痛中的效果,寻找苏芬太尼较为理想的配伍剂量.方法 年龄30～60岁,ASA ......
目的 观察亚麻醉剂量的氯胺酮-芬太尼辅助区域麻醉的临床效果及安全性.方法 选取各类需要择期进行腹部或者四肢手术的患儿90例,并......
目的对“K 粉”急性中毒患者的心肌酶进行检测并探讨其临床意义,开展药学服务.方法采用 Rosalki 速率法、免疫抑制法分别检测“K ......
目的 比较曲马多和氯胺酮预防雷米芬太尼麻醉颅脑手术患者术后痛觉过敏的效果.方法行颅脑幕上肿瘤切除术患者150例,按随机数字表......
Application and Assessment of Ketamine-Xylidinothiazoline Combinations for Anaesthesia in Rhesus Mon
The quantitative anaesthesia assessment technique was used to evaluate the effectiveness of ketamine, ketaminexylidinoth......
目的 探讨丙泊酚复合亚麻醉剂量氯胺酮在分娩镇痛中的应用.方法 选择自然分娩产妇120例,采用随机数表法分为对照组和观察组.对照组......
目的 观察右美托咪定(DEX)在小儿腹股沟斜疝手术镇静效果及对氯胺酮基础麻醉的不良反应的影响.方法 80例行腹股沟斜疝修补手术的患......
目的探讨氯胺酮、丙泊酚复合芬太尼用于小儿手术麻醉的可行性与安全性。方法将择期拟行手术的70例患儿按照随机数字表法分为两组,......
目的 观察盐酸戊乙奎醚-氯胺酮-丙泊酚静脉麻醉复合局部浸润麻醉方法用于先天性心脏病(CHD)经导管封堵术中的效果.方法 选择86例先......
目的 探讨小剂量氯胺酮预先静脉注射对蛛网膜下隙与硬膜外腔联合阻滞麻醉下剖宫产手术患者寒战预防的有效性和安全性.方法 90例拟......
